Peppermint (Mentha x piperita) is a plant in the mint family. It’s a natural hybrid of spearmint and wild mint. The leaf and oil are used as medicine.Among several plants, Mentha piperita is one of the herbs most widely used worldwide, with a long history of safe use in medicinal preparations.Its leaf is used as a remedy for common cold, inflammation of the mouth, pharynx, liver, as well as disorders in the gastrointestinal tract such as nausea, vomiting, diarrhea, cramps, flatulence and dyspepsia.This plant possess polyphenols that are highly effective antioxidants and are less toxic than the synthetic ones.This property makes it of great interest to the Food Industry, since the phenolic compounds retard the oxidative degradation of lipids improving the quality and nutritional value of food. It is used to add flavor or fragrance to foods, cosmetics, soaps, toothpastes, mouthwashes, and other products, and it may have some medicinal uses.Peppermint (Mentha piperita) leaves can be used dried or fresh in teas.People use peppermint for irritable bowel syndrome (IBS). It is also used for indigestion, bed sores, tension headache, anxiety, insomnia, memory, and many other purposes, but there is no good scientific evidence to support many of these uses.This plant has demonstrated the presence of a wide variety of bioactive compounds that represent a rich resource in phytochemicals of great interest to treat several pathologies.Some of the benefic biological effects show that this plant may play an important role as antioxidant, antinociceptive, anti inflammatory, antimicrobial, anti-carcinogenic, antiviral, anti-allergic and antitumorigenic, indicating its utility in the prevention or treatment of several diseases. Herbal medicinal compounds are used all over the world as the most natural way to intake of phytochemicals. The use of natural products that are rich in bioactive substances is growing along with the demand for plants containing wide range of antioxidant properties and bioactive molecules capable of neutralizing free radicals slowing the progress of many chronic diseases associated with oxidative stress.